New reasons for sleep
Why do animals sleep? Why is half of human life spent on sleeping? Do all living things need sleep? What good can sleep bring to us?
Scientists from Israel have solved the mystery by finding that sleep increases the movement of chromosomes and reduces the accumulation of DNA damage in neurons.
By imaging in real time the chromosomal markers in individual cells of living zebrafish, the researchers found that sleep increased the chromosomal dynamics of individual neurons, but had no effect on the other two types of cells.
By manipulating sleep, chromosomal kinetics, neuronal activity, and DNA double-strand disruption (DSBs), the researchers found that the number of DSBs increased when the chromosomal kinetics were low without sleep. Sleep, in turn, increases the kinetics of chromosomes, which is crucial to reducing the number of DSBs.
These results suggest that sleep helps maintain the stability of chromosomes in the nucleus.
We now have a causal relationship between sleep, chromosomal dynamics, neuronal activity, and DNA damage and repair. Sleep helps animals by reducing the accumulation of DNA damage. Although animals are less alert to their surroundings when they sleep, it helps them by making chromosomes in their nuclei more stable. Same for people, who lose some of their activity time, but by using that time to rest their neurons, it’s going to have a more positive effect on our non-sleep time.
Here are some DNA damage-related ELISA Kits.
Human DNA Damage Inducible Transcript 3 (DDIT3) ELISA Kit https://dldevelop.com/Research-reagent/dl-ddit3-hu.html
Mouse DNA Damage Inducible Transcript 3 (DDIT3) ELISA Kit https://dldevelop.com/Research-reagent/dl-ddit3-mu.html
Scientists from Israel have solved the mystery by finding that sleep increases the movement of chromosomes and reduces the accumulation of DNA damage in neurons.
By imaging in real time the chromosomal markers in individual cells of living zebrafish, the researchers found that sleep increased the chromosomal dynamics of individual neurons, but had no effect on the other two types of cells.
By manipulating sleep, chromosomal kinetics, neuronal activity, and DNA double-strand disruption (DSBs), the researchers found that the number of DSBs increased when the chromosomal kinetics were low without sleep. Sleep, in turn, increases the kinetics of chromosomes, which is crucial to reducing the number of DSBs.
These results suggest that sleep helps maintain the stability of chromosomes in the nucleus.
We now have a causal relationship between sleep, chromosomal dynamics, neuronal activity, and DNA damage and repair. Sleep helps animals by reducing the accumulation of DNA damage. Although animals are less alert to their surroundings when they sleep, it helps them by making chromosomes in their nuclei more stable. Same for people, who lose some of their activity time, but by using that time to rest their neurons, it’s going to have a more positive effect on our non-sleep time.
Here are some DNA damage-related ELISA Kits.
Human DNA Damage Inducible Transcript 3 (DDIT3) ELISA Kit https://dldevelop.com/Research-reagent/dl-ddit3-hu.html
Mouse DNA Damage Inducible Transcript 3 (DDIT3) ELISA Kit https://dldevelop.com/Research-reagent/dl-ddit3-mu.html
